Neohesperidin is a natural flavonoid extracted from plants in the Brassicaceae family (e.g., limes, Citrus aurantium) with a variety of biological activities and a wide range of applications.<\/p>\n\n\n\n
1. Basic information<\/p>\n\n\n\n
Chinese name: Neohesperin<\/p>\n\n\n\n
English name: Neohesperidin<\/p>\n\n\n\n
CAS No.: 13241-33-3<\/p>\n\n\n\n
Molecular formula: C\u2082\u2088H\u2083\u2084O\u2081\u2085<\/p>\n\n\n\n
Molecular weight: 610.56 g\/mol<\/p>\n\n\n\n
Properties: white crystalline powder, melting point 236\uff5e237\u2103, easily soluble in hot water and hot ethanol, insoluble in ether.<\/p>\n\n\n\n
2. Biological Activity<\/p>\n\n\n\n
Antioxidant:<\/p>\n\n\n\n
In 1.1-diphenyl-2-trinitrophenylhydrazine (DPPH) radical scavenging assay, the IC\u2085\u2080 was 22.31 \u03bcg\/mL, showing strong antioxidant capacity.<\/p>\n\n\n\n
Anti-inflammatory and anti-allergic:<\/p>\n\n\n\n
Inhibit the release of inflammatory mediators and alleviate allergic reactions.<\/p>\n\n\n\n
Regulation of Glycolipid Metabolism:<\/p>\n\n\n\n
Inhibit adipocyte differentiation, reduce triglyceride content, activate Akt\/GSK3\u03b2 signaling pathway.<\/p>\n\n\n\n
Protect gastric mucosa:<\/p>\n\n\n\n
Significantly inhibits HCl\/ethanol-induced gastric damage, reduces gastric acid secretion and elevates gastric juice pH.<\/p>\n\n\n\n
Anti-tumor:<\/p>\n\n\n\n
Inhibits the growth of leukemia cells (e.g., Caco-2. CEM\/ADR5000. CCRF-CEM) with IC\u2085\u2080 values of 0.17. 0.17. and 0.12 mM, respectively.<\/p>\n\n\n\n
3. Application areas<\/p>\n\n\n\n
Food industry:<\/p>\n\n\n\n
As a natural sweetener, the sweetness is 1000 times that of sucrose (derivatives after hydrogenation can reach 1500-2000 times), suitable for fruit juice, beverage, pastry, etc., especially for diabetic patients.<\/p>\n\n\n\n
Pharmaceutical field:<\/p>\n\n\n\n
Used in drug formulations for the treatment of cardiovascular diseases, anti-inflammatory, antioxidant and regulation of glycolipid metabolism.<\/p>\n\n\n\n
Cosmetics:<\/p>\n\n\n\n
Utilizing its antioxidant and anti-inflammatory properties to develop anti-aging and whitening products.<\/p>\n","protected":false},"excerpt":{"rendered":"
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