{"id":1902,"date":"2025-06-02T22:00:00","date_gmt":"2025-06-02T14:00:00","guid":{"rendered":"https:\/\/neohesperidine.com\/?p=1902"},"modified":"2025-06-06T13:45:21","modified_gmt":"2025-06-06T05:45:21","slug":"bioactivity-and-pharmacology-of-neohesperidin","status":"publish","type":"post","link":"https:\/\/neohesperidine.com\/?p=1902","title":{"rendered":"Bioactivity and Pharmacology of Neohesperidin"},"content":{"rendered":"\n<p>Hesperidin has a variety of biological activities and pharmacological effects, as follows:<\/p>\n\n\n\n<p>Antioxidant effect: Hesperidin has significant antioxidant properties, can scavenge free radicals in the body, inhibit lipid peroxidation, reduce oxidative stress-induced damage. It can enhance the cellular antioxidant defense ability by up-regulating the activity of antioxidant enzymes (such as superoxide dismutase SOD, catalase CAT and glutathione peroxidase GSH-Px). In addition, neohesperidin can reduce the production of free radicals by chelating metal ions.<\/p>\n\n\n\n<p>Anti-inflammatory and immunomodulation: Neohesperidin can inhibit the expression of inflammatory factors, such as tumor necrosis factor-\u03b1 (TNF-\u03b1), interleukin-6 (IL-6) and so on, to alleviate chronic inflammatory response. It reduces tissue damage caused by inflammation by inhibiting inflammatory pathways such as NF-\u03baB and regulates the activity of immune cells to improve allergic reactions.<\/p>\n\n\n\n<p>Cardiovascular protection: Neohesperidin has a protective effect on the cardiovascular system, lowering blood lipid levels, inhibiting platelet aggregation, improving vascular endothelial function, and reducing the risk of atherosclerosis. It can also regulate blood pressure, enhance the elasticity of blood vessels, and prevent the occurrence of cardiovascular disease.<\/p>\n\n\n\n<p>Metabolic Regulation: Neohesperidin shows potential in metabolic regulation, promoting glucose and lipid metabolism and aiding in the control of blood glucose and body weight. It aids in the management of diabetes and obesity by affecting insulin sensitivity and glucose metabolism.<\/p>\n\n\n\n<p>Neuroprotective: Neohesperidin is neuroprotective, crossing the blood-brain barrier and reducing neuroinflammation and oxidative stress associated with neurodegenerative diseases. It protects nerve cells from damage and slows the progression of neurodegenerative diseases through antioxidant and anti-inflammatory mechanisms.<\/p>\n\n\n\n<p>Antibacterial and antiviral: Neohesperidin has an inhibitory effect on a wide range of bacteria and viruses, and is able to enhance the body&#8217;s immune function and improve resistance to infections.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Hesperidin has a variety of biological activities and p [&hellip;]<\/p>\n","protected":false},"author":3,"featured_media":1903,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-1902","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-industry-news"],"_links":{"self":[{"href":"https:\/\/neohesperidine.com\/index.php?rest_route=\/wp\/v2\/posts\/1902","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/neohesperidine.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/neohesperidine.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/neohesperidine.com\/index.php?rest_route=\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/neohesperidine.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=1902"}],"version-history":[{"count":1,"href":"https:\/\/neohesperidine.com\/index.php?rest_route=\/wp\/v2\/posts\/1902\/revisions"}],"predecessor-version":[{"id":1904,"href":"https:\/\/neohesperidine.com\/index.php?rest_route=\/wp\/v2\/posts\/1902\/revisions\/1904"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/neohesperidine.com\/index.php?rest_route=\/wp\/v2\/media\/1903"}],"wp:attachment":[{"href":"https:\/\/neohesperidine.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=1902"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/neohesperidine.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=1902"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/neohesperidine.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=1902"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}