Neohesperidine applications mainly include food industry, pharmaceutical field, daily chemical industry and feed additives, etc., the following is a specific introduction:
Food industry
Sweetener: Neohesperidine dihydrochalcone, obtained by hydrogenation, is 1500~2000 times sweeter than sucrose, and is widely used in fruit juices, fruit wines, beverages, pastries and low-calorie foods, especially for diabetic patients. Its sweetness presents slowly but lasts long, with a pleasant aftertaste, and can also be compounded with saccharin to shield the metallic aftertaste.
Food additives: Neohesperidine dihydrochalcone has the characteristics of sweetening, aroma, flavor and masking the bitter taste, etc. It is listed in the hygienic standard varieties for the use of food additives by the Ministry of Health, and can be used in the food industry.
Pharmaceutical field
Flavor enhancer: Neohesperidine dihydrochalcone can be used as a flavor enhancer to mask the bitter taste of drugs, and its antioxidant activity is remarkable (DPPH radical scavenging IC₅₀ 22.31 μg/mL), which can play a dual role in pharmaceutical preparations.
Pharmaceutical ingredients: Neohesperidine has biological activities such as regulating blood lipids, preventing cardiovascular diseases and antioxidant, and can be used in the preparation of lipid-lowering drugs and drugs for the prevention of cardiovascular diseases.
Daily chemical industry
Cosmetic raw materials: Hesperidin (and Neohesperidine with flavonoids) with antioxidant, anti-inflammatory, antibacterial and other effects, in cosmetics as skin conditioning agent, antioxidant and emollient agent used to improve the quality of the skin, reduce wrinkles and pigmentation, and the risk factor is low, high safety.
Feed additives
Growth promoter: Neohesperidine dihydrochalcone enhances piglets’ appetite, promotes growth and reduces feed consumption, while attenuating or removing the bitter taste of feed additives such as erythromycin, sulfadiazine and tetracycline. The annual demand for this product in the European feed industry is more than 100 tons, corresponding to the consumption of Neohesperidine more than 100 tons.